FUNCTIONAL ANALYSIS OF THE CATHEPSIN-LIKE CYSTEINE PROTEASE GENES IN ADULT BRUGIA MALAYI USING RNA INTERFERENCE.

Functional analysis of the cathepsin-like cysteine protease genes in adult Brugia malayi using RNA interference.

Cathepsin-like enzymes have been identified as potential targets for drug or Drawing Tablet vaccine development in many parasites, as their functions appear to be essential in a variety of important biological processes within the host, such as molting, cuticle remodeling, embryogenesis, feeding and immune evasion.Functional analysis of Caenorhabdi

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Prognostic Value and Implication for Chemotherapy Treatment of ABCB1 in Epithelial Ovarian Cancer: A Meta-Analysis.

BACKGROUND:Chemotherapy resistance is reported to correlate with up-regulation of anti-tumor agent transporter ABCB1 (p-gp) in epithelial ovarian cancer (EOC), but the results remain controversial.To reconcile the results, a systematic review followed by meta-analysis was performed to assess the association between high ABCB1 status or ABCB1 gene v

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Trends in Reproductive Indicators of Green and Hawksbill Sea Turtles over a 30-Year Monitoring Period in the Southern Gulf of Mexico and Their Conservation Implications

Long-term monitoring programs of species at risk are efficacious tools to assess population changes, evaluate conservation strategies, and improve management practices to ensure populations reach levels at which they can fulfill their ecological roles.For sea turtles, annual nesting beach surveys are the most accessible method to estimating the pop

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